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GLP-1 Drugs & Weight Loss
Asked: What did studies find about GLP-1 drugs and weight loss?
What the research shows
10–15%
Typical weight loss on GLP-1 drugs
Over several months, per Mayo Clinic review of the evidence [8]
Good to know
10–15% of body weight over several months [8]
Typical weight loss
About 11% vs 7% of starting weight [3]
Women vs men
Lower dementia and addiction risk; higher kidney, pancreas and GI problems
Also linked to
Focus the findings
Across trials, GLP-1 receptor agonists consistently produced clinically meaningful weight loss. A systematic review found % of liraglutide users and % of semaglutide users lost weight, and a Johns Hopkins analysis reported average losses of about 11% of starting weight in women versus about 7% in men. [3]